Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine cautions Why plaquenil is good for lupus Plaquenil “ Side Effects Dizzy, upset stomach, back pain and side pain, abdominal cramps, leg cramps, rapid heart rate, anxiety and body felt covered in bruises Before taking Plaquenil my only symptom. Aug 18, 2009 Ginny, I had some very minor diarrhea, nausea, cramping for about a week when I started Plaquenil. Everyone is different, but for me, taking the med about 15 min. after eating, rather than before or with a meal, makes things much easier on my stomach, even for just Advil. Common side effects Nausea and diarrhea This can often can be combatted by taking Plaquenil with food or milk. Dizziness Precautions with this side effect Do not drive, use machinery. Cramps. Headache. Dry skin. Loss of appetite. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Cramps and plaquenil Stomach cramps from Plaquenil - what to do? Lupus Forums., Plaquenil = explosive diarrhea - Hydroxychloroquine half lifePlaquenil mid back pain Apr 10, 2019 Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil Uses, Dosage & Side Effects -. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Compare Plaquenil vs Chloroquine -. Lupus myositis often affects the muscles of your neck, pelvis, thighs, shoulders and upper arms; difficulty in climbing stairs and getting up from a chair are early symptoms. Later symptoms may include difficulty lifting objects onto a shelf, lifting your arm to comb or brush your hair, getting out of the bath. I've been on Plaquenil for almost 2 wks now and I'm also taking Prednisone, could one of these be causing my extreme stomach cramps? 2 nights ago, I had a cheeseburger and mac and cheese and I thought I was going to die about 1 in the morning. I ended up throwing up once and then I had diarrhea for a bit and then it passed once my system cleared. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others.