I don't get many side effects generally, but with prednisone I DO. It does help, but this can't be a long term affair. Plaquenil is a great drug (I have no experience with it, but many people with lupus take it). I'd ask your rheumy about it and have them explain why they made that choice for you. Prednisone is an intermediate acting corticosteroid-which means it has direct anti-inflamitory properties that take effect begining in a few hours. Is plaquenil another option instead of the prednisone? It is ment to get this undercontrol now and diminish your pain. Sweating stoping plaquenil Plaquenil cost increase Prednisone is a bone killer as I’m paying the price 25 years later, but I was pretty pain free all those years! No hair loss and plaquenil has not affected my eyes other than dry eyes. Keep a diary of your meds. Background/Purpose Antiphospholipid antibodies in SLE may be changed by treatment, but past studies have been conflicting. We examined the impact of starting or stopping two treatments hydroxychlorquine and prednisone on levels of antiphospholipid antibodies. Methods 943 SLE patients, who had at least 10 quarterly visits for testing for each anticardiolipin isotype IgG, IgM and IgA Drug interactions are reported among people who take Prednisone and Hydroxychloroquine sulfate together. This study is created by eHealthMe based on reports of 3,854 people who take Prednisone and Hydroxychloroquine sulfate from Food and Drug Administration FDA, and is updated regularly. It has not direct anti-inflamitory properties and instead works on the immune system-though the mechanism is not known. Plaq is a longer time medication it may take two months before their is a noticable difference. Hydroxychloroquine and prednisone Prednisone/Plaquenil question -, Hydroxychloroquine and Prednisone Have Different Effects on. Hydroxychloroquine cheapPlaquenil antimalarialPhotoreceptor integrity line plaquenilPlaquenil photosensitivity rash Sjogren's Syndrome Hydroxychloroquine - Painful Muscles Of Legs. I have been on 400mg of Plaquenil for 7 months now, but for the last 2 months I have been experiencing muscle problems in my legs, it is so painful that I am yelling out with pain. I stopped taking the Plaquenil and the muscle problems stopped. Autoimmune Diseases Prednisone And Hydroxychloroquine 200 Mg?. Prednisone and Hydroxychloroquine sulfate drug interactions.. Plaquenil vs Prednisone for PMR Polymyalgia Rheumatica.. Rated Hydroxychloroquine for Rheumatoid Arthritis Report. i started on 400 mg of hydroxychloroquine 400 mg daily along with prednisone 10mg daily 9 weeks ago. The GI upset started after a short. May 11, 2016 Hi @charlena that is good your husband has been able to get off of prednisone as I see in your past posts that he has struggled to make that transition. @kimdett has mentioned taking both prednisone and hydroxycholorquine Plaquenil in the past and @boomerexpert has mentioned taken hydroxycholorquine and they may be able to share their experience. I started with plaquenil last year, yes it took almost 6 months to get a level in your body, it does help, trust me. I was on Prednisone 7.5 to 10 mg per day, had a bad flair up and I am on 40 mg per day, last Friday the dr.''s told me to go down by 5 mg per week, so from 40mg to 35 mg per day.