Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Chloroquine and parkinson's disease Silver and chloroquine Taking methotrexate with hydroxychloroquine has not been studied. It may increase your risk of side effects. Taking cyclosporine with hydroxychloroquine can increase the amount of cyclosporine in. Compare Hydroxychloroquine vs. Methotrexate, which is better for uses like RA, Lupus and Arthritis. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Methotrexate is a disease-modifying anti-rheumatic drug DMARD that is used to reduce the swelling and pain associated with certain diseases like rheumatoid arthritis, psoriatic arthritis, vasculitis, juvenile arthritis and lupus. More and more doctors are using methotrexate to treat lupus when antimalarials like hydroxychloroquine Plaquenil or nonsteroidal anti-inflammatory drugs aren’t. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Methotrexate trexall and hydroxychloroquine plaquenil Managing the Medicine Cabinet, Compare Hydroxychloroquine vs Methotrexate - Comprehensive. Is plaquenil a steroidPlaquenil and weight lossChloroquine pi3 kinasePlaquenil hydroxychloraquineDoes plaquenil increase the likelihood of getting a cold Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and. Methotrexate vs Plaquenil Comparison -. Methotrexate - Kaleidoscope Fighting Lupus. Plaquenil vs. Rheumatrex, Trexall Prescription Treatment for.. Methotrexate–hydroxychloroquine combination therapy may cause lower disease activity in early RA than methotrexate monotherapy. Methotrexate monotherapy as first early RA treatment seems to lead to more treatment intensification. I was diagnosed with RA in march and have been on increasing dose of methotrexate. Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Thanks Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs.