Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data. Plaquenil for psoriatic arthritis Plaquenil with zyban Plaquenil for hashimoto's Background and objectives Hydroxychloroquine is widely used in patients with rheumatoid arthritis. However, large-scale studies examining the long-term effects of hydroxychloroquine on the development of kidney disease in patients with rheumatoid arthritis are lacking. Hydroxychloroquine Plaquenil and sulfasalazine Azulfidine are used for mild rheumatoid arthritis. They are not as powerful as other disease-modifying antirheumatic drugs, but they usually cause fewer side effects. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Please check with the appropriate physician regarding health questions and concerns. The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Hydroxychloroquine and rheumatoid arthritis Treatments for Rheumatoid Arthritis, What are the side effects of hydroxychloroquine and. What class of medication is plaquenilSulfasalazine plaquenilHydroxychloroquine pigmentation histology Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. When the first biologic DMARD received FDA-approval in 1998, and as other biologics followed in subsequent years, it appeared as though Plaquenil would become less prescribed. Taking Plaquenil for Rheumatoid Arthritis. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Hydroxychloroquine Side-effects, uses, time to work. Also called Plaquenil, hydroxychloroquine is a disease-modifying drug that can help decrease both the swelling and pain of rheumatoid arthritis. According to, there is not a clear reason why hydroxychloroquine is so effective in treating autoimmune diseases. For lupus erythematosus, one or two tablets are usually taken once or twice daily. For rheumatoid arthritis, one to three tablets are usually taken once a day. Hydroxychloroquine can be taken with a glass of milk or a meal to decrease nausea. Follow the directions on your prescription label carefully. Highlights for hydroxychloroquine Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis.