It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil causes skin rash Chloroquine cell toxicity Hydroxychloroquine sulphate tabletsrheumatoid arthritis TY - JOUR. T1 - Hydroxychloroquine-induced cardiomyopathy a case report. AU - Muthukrishnan, Preetika. AU - Roukoz, Henri. AU - Grafton, Gillian To the Editor Chloroquine CQ and hydroxychloroquine HCQ are widely used in the longterm treatment of connective tissue disease CTD and are usually considered safe1. However, these therapies may cause serious adverse events2, including cardiac toxicity3. The cardiomyopathy induced by an antimalarial drug might mimic the cardiac involvement of Fabry disease FD, a genetic storage. Drug-induced cardiotoxicity including chemotherapy-induced cardiotoxicity remains an important cause of heart disease and heart failure.1, 2, 3 Cardiomyopathy from cancer chemotherapy is well recognized as a drug-induced complication but the cardiotoxicity from other drugs is not well described.2, 3 Chloroquine CQ and hydroxychloroquine HCQ are 4-aminoquinolines 4 at one time commonly used. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Hydroxychloroquine induced cardiomyopathy and heart failure in twins Chemotherapy Induced Cardiomyopathy - The Cardiology Advisor, Heart Involvement in a Woman Treated with Hydroxychloroquine. Hydroxychloroquine hearburnIs chloroquine an effective antimalarial drug in brazil Peripartum cardiomyopathy is a rare type of heart occurs during pregnancy or immediately after delivery. The condition weakens the heart muscle and causes the heart to become enlarged. Peripartum Cardiomyopathy Causes, Symptoms, and Diagnosis. Hydroxychloroquine-Induced Cardiomyopathy Case Report.. Hydroxychloroquine SpringerLink. Abstract. Chloroquine Hydroxychloroquine-induced cardiomyopathy is a rare but potentially life-threatening condition. Cessation of the culprit drug, along with aggressive afterload reduction therapy, has been associated with halting of disease progress and even improvement in patients' clinical and histologic status. Although the precise incidence is unknown, drug-induced myopathy is among the most common causes of muscle disease. Drug-induced myopathy ranges from mild myalgias with or without mild weakness to chronic myopathy with severe weakness and to massive rhabdomyolysis with acute renal failure. On the basis of these classic findings, a diagnosis of hydroxychloroquine cardiomyopathy was made, and the drug was discontinued. Three months later her symptoms had completely resolved. Repeat imaging using cardiac magnetic resonance demonstrated an ejection fraction of 65% D, Online Video 2.