Additionally, another exception occurred while executing the custom error page for the first exception. This article focuses upon hydroxychloroquine retinopathy. Chloroquine was originally used as an anti-malarial therapeutic. Is plaquenil a steroid an immunosuppressant Can hydroxychloroquine cause mental problems Hydroxychloroquine side effects skin rash Is plaquenil a steroid Objectives To compare different screening procedures for hydroxychloroquine sulfate Plaquenil toxicity at different stages of damage. Methods Ten patients were studied using 10-2 automated fields, multifocal electroretinography, spectral domain optical coherence tomography SD-OCT, and fundus autofluorescence. Early annual screening for patients that have risk factors for developing hydroxychloroquine toxicity. SIGNS. Early signs visual field defects on 10-2 HVF usually paracentral, perifoveal and parafoveal thinning of the retina with loss of the inner/outer segment junction on SD-OCT, increased or decreased signal on autofluorescence, central/paracentral ERG depression on mfERG, +/- changes on Amsler grid, +/- subtle RPE changes, +/- decreased color vision Toxicity was found in 150 of these patients with a high-risk dosage history, as determined by clear parafoveal scotomas between approximately 2 and 6 degrees on 10-2 fields or clear parafoveal thinning and damage on SD-OCT in the same parafoveal region, along with other confirmatory data when available, including fundus images, mfERG, and FAF. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. 10-2 visual fields in plaquenil toxicity Humphrey Visual Field Findings in Hydroxychloroquine Toxicity, Hydroxychloroquine Plaquenil Toxicity and. What percent of people with arthritis benefit from plaquenilHydroxychloroquine brand name canada Visual fields. In early cases of Plaquenil toxicity, an early indicator of damage is the appearance of a paracentral scotoma seen on automated visual field testing in the absence of fundus changes. 18 Each of the testing strategies can be used to detect early toxicity changes, but the presentation of the visual field effects will vary. Due to. How to Succeed in Plaquenil Screenings. Disparity between Visual Fields and Optical Coherence.. PDF Scotoma analysis of 10-2 visual field testing with a.. Early annual screening for patients that have risk factors for developing hydroxychloroquine toxicity. SIGNS. Early signs visual field defects on 10-2 HVF usually paracentral, perifoveal and parafoveal thinning of the retina with loss of the inner/outer segment junction on SD-OCT, increased or decreased signal on autofluorescence, central. To quantify the variability of scotomas detected by 10–2 visual field VF testing with a red target in patients taking hydroxychloroquine without and with retinopathy. Retrospective review of clinical charts and VFs. Twenty-four patients taking. Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is.