If a patient is overweight, one should use the ideal body weight to assess whether the doaily dose is in the toxic range (/= 6.5 mg/kg/day). This graph shows various formulas that have been proposed for deriving ideal body weight for women, because virtually all cases of hydroxychloroquine toxicity have been female. Side effects bruising methotrexate plaquenil What are the side effects of discontinuing plaquenil Child dosage ages 0–17 years Acute attack Dosage is based on body weight. The typical starting dose is 13 mg/kg maximum dose 800 mg. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. One kilogram kg equals 2.2 pounds. Women with lupus who are OVER their ideal body weight should go by these dosing rules 5’ 7” or higher - up to 400 mg Plaquenil daily; 5’ 1/2” to 5. A daily dose of 6.5mg/kg ideal body weight places patients at higher risk, but a daily dose below this level did not preclude the patient from developing toxicity after many years of treatment. A cumulative dose of 1000g of hydroxychloroquine or 460g of chloroquine was likely the largest risk factor, which was typically achieved after 5-7. For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. The usual hydroxychloroquine dose that is prescribed is 400 mg/day. Plaquenil dosing ideal body weight Rx Side Effects New Plaquenil Guidelines and More., Protecting your eyesight when taking Plaquenil Lupus Foundation of. Can hydroxychloroquine cause mental problems The 2011 guidelines suggested a maximum dose of 6.5 mg/kg of ideal weight. The biggest difference between the 2011 and current recommendations is the need for patients to be dosed by their real weight instead of their ideal weight. Despite Plaquenil dosing recommendations, retinal toxicity.. Hydroxychloroquine Plaquenil Toxicity and.. Protecting your eyesight when taking Plaquenil Lupus.. SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day. Our results support the prescription of hydroxychloroquine based on actual capped at 400 mg per day rather than ideal body weight and did not demonstrate differences in blood levels in those who. The median weight was 160 pounds 72.7 kg, IQR 133, 185 pounds, range 90, 330 pounds. Twenty-nine percent of women were less than or equal to 63 inches tall 160 cm, a threshold height for potentially toxic dosing based on consumption of 400 mg hydroxychloroquine per day and a commonly used IBW algorithm.