So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Generic plaquenil side effects Hydroxychloroquine with or without food Lupus fog plaquenil I can tell you that plaquenil is the safest of all of the DMARDs. If you're going to stay on a DMARD for a long time, plaquenil is the one to be on. Best of luck on the plaquenil. Pills should only be split in half, not into smaller portions, such as thirds or quarters. The easiest pills to split are relatively flat round ones with a scored center, a slightly indented line that runs across the center of the pill. However, not every pill that has a scored center is meant to be split. Splitting tablets in half is a practice that some patients, employers, healthcare providers, and even health insurance and managed care companies are now recommending. Tablet splitting under the direction of a healthcare provider can be safe and save you money, too. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Can you break plaquenil in half Plaquenil hydroxychloroquine 200mg is it causing itchy., Pill splitting which ones are safe to divide? – Heart Sisters Hydroxychloroquine toxicityHydroxychloroquine and beerMefloquine chloroquine I wouldn't break them in half, the medication that comes in a single pill without score mark, shouldn't be crushed or broken in half. You should check with your pharmacist though Reply Breaking pills in half hydrochloroquine/plaquinil? - LUPUS UK. Pill Splitting - A Safe Way to Save Healthcare Dollars?. Hair loss and Plaquenil? DailyStrength. If you are taking hydroxychloroquine for symptoms of rheumatoid arthritis, your symptoms should improve within 6 months. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you. Oct 14, 2015. It’s not just an urban legend—you really can break your penis. But since there aren’t any actual bones in your boner, it’s not quite the same injury as, say, fracturing your arm. The condition is known as a penile fracture, and it occurs when your erect penis sustains some kind of force. With the Plaquenil I don't think you will find much relief in such a short time on it & at half of a workable dose. I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly.