Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality. Plaquenil male fertility Plaquenil toxicity macula Can a patient on plaquenil get the varicella vaccine Chloroquine is a medication first developed as an anti-malarial that has been used for many years to help treat lupus systemic lupus erythematosus, or SLE and rheumatoid arthritis. If a patient responds to treatment with an anti-malarial, in general it will continue to be used indefinitely. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus. Hydroxychloroquine and chloroquine phosphate have shown beneficial effects in treating discoid lupus erythematosus DLE. Additionally, The antimalarial drugs may prevent the development of systemic lupus erythematosus SLE in patients with DLE, and they might decrease the risk of cardiovascular disease. Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids. Chloroquine lupus erythematosus PAN Foundation - Systemic Lupus Erythematosus, Chloroquine - Wikipedia Hydroxychloroquine ms Jul 30, 2019 Most of the patients described were African or of African descent with dark skin who had been exposed to the sun. One was a Hispanic patient who developed vitiligo-like skin depigmentation after 1 month of chloroquine therapy for cutaneous lupus erythematosus. The skin rapidly repigmented after discontinuation of chloroquine therapy. Chloroquine Side Effects Common, Severe, Long Term -. Discoid Lupus Erythematosus Medication Antimalarial agents.. Systemic Lupus Erythematosus SLE Symptoms, Signs.. Lupus Systemic Lupus Erythematosus or SLE Systemic lupus erythematosus is a condition characterized by chronic inflammation of body tissues caused by autoimmune disease. Lupus can cause disease of the skin, heart, lungs, kidneys, joints, and nervous system. When only the skin is involved, the condition is called discoid lupus. Hydroxychloroquine and chloroquine phosphate have shown beneficial effects in treating discoid lupus erythematosus DLE. Additionally, The antimalarial drugs may prevent the development of systemic lupus erythematosus SLE in patients with DLE, and they might decrease the risk of cardiovascular disease. Alternative therapies, anecdotal reports, and small, open-label trials as reported by. Detailed Hydroxychloroquine dosage information for adults and children. Includes dosages for Rheumatoid Arthritis, Systemic Lupus Erythematosus, Malaria Prophylaxis and more; plus renal, liver and dialysis adjustments.