In many cases, once the offending drug has been stopped, fading of the lesions occurs. However, the pigmentation may last a long time or become permanent. Plaquenil dissolving immune complexes Can plaquenil cause weight gain We report two cases of hydroxychloroquine-induced hyperpigmentation presenting in a 50-year-old Caucasian female case 1 and a 78-year-old female case 2, both receiving 400 mg per day. Case 1 had an arthritis predominant undifferentiated connective tissue disease, which was treated with hydroxychloroquine for 4-5 years. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Applies to hydroxychloroquine oral tablet Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Skin, the largest organ of the human body, is a mirror of your health. Because many drugs that induce skin pigmentation also cause photosensitivity reactions, sun protection is usually recommended. Plaquenil associated hyperpigmentation Common and Rare Side Effects for Plaquenil Oral, Plaquenil Hydroxychloroquine - Side Effects, Dosage. How to treat nausea from plaquenilImuran plaquenil together headache Hydroxychloroquine HCQ-associated hyperpigmentation is uncommon, with onset ranging from 3 months to 22 years following the initiation of therapy1. A 32-year-old woman presented with a 1.5-year history of symmetric polyarthritis, positive rheumatoid factor, and anticyclic citrullinated peptide antibody, without erosive joint changes. Hydroxychloroquine-induced Hyperpigmentation of the Skin.. Hydroxychloroquine Side Effects Common, Severe, Long Term -. Hydroxychloroquine toxicity - EyeWiki. Lichen planus pigmentosus LPP is a rare form of lichen planus. It is characterized by oval or irregularly-shaped brown to gray-brown macules and patches on the skin. Areas that are exposed to sun such as the forehead, temples and neck are most commonly affected. Ventricular arrhythmias and torsade de pointes have been reported with the use of hydroxychloroquine. Beta-agonists may be associated with adverse cardiovascular effects including QT interval prolongation, usually at higher doses, when associated with hypokalemia, or when used with other drugs known to prolong the QT interval. Hydroxychloroquine Plaquenil is an older DMARD sometimes still used for mild RA. It may work by interrupting signaling among cells. It’s one of the best tolerated DMARDs. Side effects are usually mild and may include nausea and diarrhea. Taking the drug with food may help. Changes to the skin are less common.