Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil history Does plaquenil increase the likelihood of getting a cold How to stop diarrhea caused by hydroxychloroquine Bull’s Eye Retinopathy Early macular toxicity can cause stippling or mottling of the RPE Next, granular pigmentation and loss of the normal foveal reflex can occur It’s believed but not proven that if early macular changes are detected and the medication is stopped, any toxicity that has occurred can be reversed.1 If the maculopathy continues to progress, concentric zones of. The characteristics of patients which may increase of developing toxicity symptoms while taking Plaquenil include an age of more than 60 years old, having renal or hepatic insufficiency or any existing macular degeneration and retinal disease 1. Today, Plaquenil and other antimalarials are also used to treat and help prevent symptoms caused by certain autoimmune diseases such as rheumatoid arthritis RA, systemic lupus erythematosus, and discoid lupus, even though these diseases are not caused by malaria parasites. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil retinopathy symptoms Eye screening for patients taking hydroxychloroquine., Plaquenil Toxicity - Symptoms, Treatment, Risk Factors. Basic description of chloroquineAutofluorescence plaquenilAralen medicineVisual field loss in plaquenil retinopathyLosing weight off of plaquenil Renal clearance in rheumatoid arthritis RA patients taking Plaquenil for at least six months seemed to be similar to that of the single dose studies in volunteers, suggesting that no change occurs with chronic dosing. Range for renal clearance of unchanged drug was approximately 16 to 30%. Plaquenil - FDA prescribing information, side effects and uses. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. This is why it is important to be examined routinely if the patient is on long term plaquenil therapy. In the later stages, the patient may notice blurred vision, loss of central vision, difficulty reading, change in color vision or change in contrast sensitivity. In the later stages, vision loss may progress even after stopping the medication. When using both these tools, keep in mind the following from Melles and Marmor’s recent study 1. “Retinal toxicity from hydroxychloroquine use cannot be completely prevented, but effective screening should recognize retinal toxicity before symptoms or significant risk of central vision loss appear ie. Highlights for hydroxychloroquine. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis.