Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Tongue swelling from plaquenil Weight loss plaquenil Signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin Loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or; hair loss. This is not a complete list of side effects and others may occur. Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine loss of appetite Hydroxychloroquine Plaquenil Side Effects & Dosage for., Hydroxychloroquine - Side Effects, Dosage, Interactions. Aralen vs plaquenilAlternative to plaquenil for sjogren'sPlaquenil is os jumction Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Hydroxychloroquine Plaquenil -. Hydroxychloroquine Side Effects - GoodRx. Find information about common, infrequent and rare side effects of Hydroxychloroquine Oral. Loss of appetite, tiredness, weakness, or headache are uncommon side effects and typically go away over time. Rare complications The greatest concern people have when taking hydroxychloroquine is related to vision. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.