Iupac name of chloroquine

Discussion in 'Chloroquine' started by moder_vip, 28-Feb-2020.

  1. Rusreach XenForo Moderator

    Iupac name of chloroquine


    It is bioactivated hepatically to its primary metabolite, N-desethylamodiaquine, by the cytochrome p450 enzyme CYP2C8. Among amodiaquine users, several rare but serious side effects have been reported and linked to variants in the CYP2C8 alleles.

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    Unless otherwise noted, the contents of the FDA website gov, both text and graphics, are not copyrighted. They are in the public domain and may be republished, reprinted and otherwise used freely by anyone without the need to obtain permission from FDA. Primaquine is a medication used to treat and prevent malaria and to treat Pneumocystis pneumonia. Specifically it is used for malaria due to Plasmodium vivax and Plasmodium ovale along with other medications and for prevention if other options cannot be used. Chloroquine is rapidly and almost completely absorbed from the gastrointestinal tract, and only a small proportion of the administered dose is found in the stools. Approximately 55% of the drug in the plasma is bound to nondiffusible plasma constituents. Excretion of chloroquine is quite slow, but is increased by acidification of the urine.

    People who are poor metabolizers of amodiaquine display lower treatment efficacy against malaria, as well as increased toxicity. CYP2C8*1 is characterized as the wild-type allele, which shows an acceptable safety profile, while CYP2C8*2, *3 and *4 all show a range of "poor metabolizer" phenotypes.

    Iupac name of chloroquine

    Chloroquine diphosphate C18H32ClN3O8P2 ChemSpider, Primaquine - Wikipedia

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  4. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth.

    • Hydroxychloroquine - Wikipedia.
    • Chloroquine - wikidoc.
    • Chloroquine phosphate - DrugBank.

    Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is Amodiaquine is a 4-aminoquinoline compound related to chloroquine. Amodiaquine was first made in 1948. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. The wholesale cost is about US$0.01 per dose as of 2014. Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase.

     
  5. kklioo Well-Known Member

    Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Hydroxychloroquine Plaquenil How is plaquenil hydroxychloroquine used to treat lupus?
     
  6. spade Guest

    Hydroxychloroquine Medicare Coverage and Co-Pay Details. HYDROXYCHLOROQUINE is used to treat rheumatoid arthritis and systemic lupus is also used to treat malaria. The lowest GoodRx price for the most common version of hydroxychloroquine is around .41, 88% off the average retail price of 7.73.

    Plaquenil hydroxychloroquine Price Comparisons.
     
  7. MIXEL Moderator

    Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

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