It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. What is hydroxychloroquine used to treat Opthalmologic complication of hydroxychloroquine Limitations of use Hydroxychloroquine is not effective against chloroquine- or hydroxychloroquine-resistant malaria strains of Plasmodium species; not recommended for treatment of complicated malaria, malaria prophylaxis in regions with chloroquine resistance, or treatment when the Plasmodium species has not been identified; hydroxychloroquine does not prevent relapses of P. vivax and P. ovale infections because it is not effective against the hypnozoite forms of these parasites. You should not use Plaquenil if you are allergic to hydroxychloroquine. Plaquenil should not be used for long-term treatment in children. To make sure Plaquenil is safe for you, tell your doctor if you have a history of vision changes or damage to your retina caused by an anti-malaria medication; Hydroxychloroquine can reduce the gastrointestinal absorption of methotrexate through local pH changes and hence lowers the bioavailability of methotrexate 38,59. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Does plaquenil change ph Plaquenil Hydroxychloroquine - Side Effects, Dosage., Plaquenil Uses, Dosage & Side Effects - How can plaquenil affect your eyesPlaquenil lupus en espanolDiscoid lupus plaquenilPlaquenil time to take effectHydroxyzine chloroquine As an antimalarial drug, hydroxychloroquine has been shown to accumulate in malaria parasite lysosomes, increasing the pH. This activity interferes with the capacity of the parasite to hemoglobin proteolysis, stopping ordinary development and parasite replication. Hydroxychloroquine Plaquenil Success, Reviews and Side.. Mechanisms of action of hydroxychloroquine and chloroquine.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.