Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Feeling weird just started taking hydroxychloroquine Chloroquine phosphate injection The only thing that changed when I took myself off of it was my diarrhea decreased. Plaquenil was initially added to "help" the sulfasalazine, but it helps me on its own, with or without the ineffective SSZ. Humira is the heavy lifter among my meds. Plaquenil, Relafen my NSAID and my pain killer all just smooth off the edges. I do know that plaquenil is generally considered the least invasive drug, generally prescribed as the first line of treatment. Methotrexate is the most commonly prescribed DMARD, but it does come with the chance of side-effects. I never had any side-effects of dire consequence, but many on this forum have. Chinese found an In Vitro activity of Plaquenil, and maybe in Vivo too but the live study is not yet published. A Professor in France got interested in doing a trial in Marseille hospital, and was agreed a few days ago to do so Pr Raoult; He is studying Plaquenil use in viral and intracellular. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil forum discussion Sjögren's Syndrome Message Board & Forum Discussions., Methotrexate or Plaquenil? DailyStrength Plaquenil treat lupusDesethyl chloroquine Mar 02, 2011 Home › Forums › General Discussion › How does Plaquenil Work ? This topic has 4 replies, 4 voices, and was last updated 8 years, 11 months ago by Fkendall. Viewing 5 posts - 1 through 5 of 5 total Author Posts March 2, 2011 at pm #305383 katiebParticipant Hi, I know quite a. Read more How does Plaquenil Work ? - Road Back Foundation. Hydroxychloroquine / Plaquenil and the Covid-19 / Coronavirus.. Mixing Mino with Plaquenil? - Road Back Foundation. Patient Forums for Sjogren's Syndrome. Part of the Bones, joints and muscles category. Symptom, treatment and advice from community members Jan 31, 2013 I decided to give Plaquenil a go though, and I have been on it for 2 weeks. You are supposed to have a blood test every month to check on your liver and kidneys as long term use can affect them. I was told also to keep an eye out for 'floaters' in my eyes, as Plaquenil can cause macular damage to your retinas. I luckily had time the day I did have unusual stomach pain in my lower right abdomen and went to an urgent care dr. Turns out I had an appendicitis very close to bursting. My surgeon thinks the plaquenil masked my symptoms and altered my immune response to the infection.