Hydroxychloroquine and chloroquine comparison

Discussion in 'Generic Chloroquine' started by ilmel, 10-Mar-2020.

  1. riderua Well-Known Member

    Hydroxychloroquine and chloroquine comparison


    It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world.

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    Hydroxychloroquine is much less active than chloroquine against chloroquine-resistant Plasmodium falciparum, in agreement with its physicochemical properties Hydroxychloroquine, an alkylated 4-aminoquinoline, is a hydroxylated form of chloroquine and has a biological mechanism of action similar to chloroquine’s. Hydroxychloroquine was originally developed as a safer alternative to chloroquine for the treatment of malaria and was later found to have antirheumatic and anti-inflammatory uses. In a recent case–control study, it was found that patients who used hydroxychloroquine were at increased risk of dementia OR 1.91 1.39–2.64 for exposure ≥305 days on comparison with no exposure.3 However, a significant risk increase was also evidenced in people using methotrexate or sulfasalazine. The effect of hydroxychloroquine on progression of dementia in early Alzheimer's.

    For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too.

    Hydroxychloroquine and chloroquine comparison

    Hydroxychloroquine Prices, Coupons & Savings Tips - GoodRx, Hydroxychloroquine Information for Providers AIDSinfo

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  5. Chloroquine Remove Chloroquine from your drug comparison. Hydroxychloroquine Remove Hydroxychloroquine from your drug comparison. View side-by-side comparisons of medication uses, ratings, cost, side effects, interactions and more.

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    Korea is using it in place of chloroquine, so it likely works similarly. The only main difference is that hydroxychloriqune seems to be slower to build up while chloroquine is much quicker. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Hydroxychloroquine has similar pharmacokinetics to chloroquine, with rapid gastrointestinal absorption and elimination by the kidneys. Cytochrome P450 enzymes CYP2D6, 2C8, 3A4 and 3A5 metabolize hydroxychloroquine to N-desethylhydroxychloroquine. Pharmacodynamics. Antimalarials are lipophilic weak bases and easily pass plasma membranes.

     
  6. bye Moderator

    Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Hydroxychloroquine Uses, Dosage & Side Effects - Hydroxychloroquine Oral Route Side Effects - Mayo Clinic
     
  7. Yashikov New Member

    Treating Lupus with Anti-Malarial Drugs Johns Hopkins. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used.

    Plaquenil Oral Uses, Side Effects, Interactions, Pictures.
     
  8. PrintScreen XenForo Moderator

    Begining Plaquenil - The plaquenil is known to cause gas and stomach issues for some people. Since I have such a sensitive GI tract my rheumy started me off slowly on it. I took 1/2 tab every other day and worked my way up to 2/200mg tabs a day within a couple of months and didn't have any problems.

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