So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Hydroxychloroquine 3d Hyperpigmentation plaquenil Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. Summary Drug interactions are reported among people who take Plaquenil and Levaquin together. This study is created by eHealthMe based on reports of 394 people who take Plaquenil and Levaquin from Food and Drug Administration FDA, and is updated regularly. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Stopping hydroxychloroquine while on levaquin Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Plaquenil and Levaquin drug interactions - eHealthMe Dmards plaquenilArtemisinin-based combination therapy chloroquine primaquine falciparum vivaCan hydroxychloroquine cause a false positive for pregnancyPlaquenil sore throatPlaquenil tooth decay I went to Conv. Care yesterday and found out I have strep The Dr. prescribed Levaquin b/c it is a strong antibiotic. Now I am having sever achiness, hot/ cold spells, waking up in the middle of the night sweating like crazy. Has anyone with Lupus been on Levaquin? Did you have a flare up? or ache really bad? Lupus and Levaquin" Lupus Community - Support Group. Let me tell you what weaning down from Plaquenil is like.. Can You Get BOTOX When Taking Antibiotics? SkinViva.. So I ran out of my plaquenil and the Rheum. that prescribed it I am no longer seeing and wont re-fill it and I dont see my new Rheum. until Decemeber 23rd. I am nervous to see what will happen. The pharmacist said there wont be any danger just stopping it. Im just nervous to see what my body will do. Has anyone gone off the plaquenil and what happened? I hear my new Rheum. is all for it so I. Plaquenil stays in your body for about 3 months. If you must stop it, it will take a while for the side effects to go away. You should have an eye examination every year to prevent a very rare but serious eye problem. Levaquin Levofloxacin Side Effects Leave Long-Lasting Disabilities. Fluoroquinolone antibiotics like Levaquin levofloxacin may have unexpected and long-lasting side effects. Joints, tendons and nerves can all be affected.