She sent me to a hematologist, who tested for a number of things that may be causing the platelets to be high. He determined that I had positive ANA with a titer count of 0. Can you take antibiotics with hydroxychloroquine Quit plaquenil breast cancer treatments Once your ANA is positive there are further blood tests than can be run to try to narrow down if it is indeed lupus. Not sure if these are the tests your doctor is running. To me with long term joint pain and muscle pain it is always good to pursue if it could be lupus as knowledge lets you treat things before they get really bad. Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. He re-did the ANA test, which returned negative this time and sent me away feeling like I had wasted both his and my time. After years of dead ends I was feeling hopeful that I was on the right track, but now it appears that I am back at square one. I have been told that healthy people can have positive ANA tests, but I am not healthy. I am very frustrated because I still have no answers regarding why the ANA count would be so high if I am testing negative for all of these autoimmune diseases. Yet, he said I was negative for the rheumatoid factor as well as a more specific Lupus test (I don't remember exactly what this test was called, something with DNA). How long plaquenil after positive ana CONDITION it’s not a sure sign of an autoimmune disease. DESCRIPTION, Lupus Medicines Hydroxychloroquine - Brigham and Women's. When was chloroquin discoveredPlaquenil brittle hair If you go to the Mayo Clinic Lupus website it will give the info on there. It can also take years for an ANA to turn positive or sometimes when you blood is drawn it is negative at that time, but it does not mean it is always negative. It took me year and years of being ill to have a positive ANA and other blood work. Lupus with negative blood work DailyStrength. Positive ANA Turned Negative - Arthritis Information. Plaquenil -. How long can you have symptoms of Lupus before tests come back positive - Hello Ladies, thanks for replying. I have been having problems for four years now. I was diagnosed first with Osteoarthritis.then Fibromyalgia. Shauna, I'm not a doctor to put it mildly. But Plaquenil could help someone ANA-negative for a few reasons that I've read about. First, maybe you do have positive ANA & positive autoantibodies, but all your bloodwork was done when those levels had fallen. Then there's that rare kind of SLE called Ro-lupus. These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives.