I have SLE and a specific form of APLS, which causes endometriosis and ovarian cysts (both of which I've had). Could somebody please tell me what statins are and what I can expect after starting these meds? There are a couple of good drug indexes out there, which I've bookmarked and use all the time. I have a list of questions ready for him before treatment with Plaquenil begins. The most useful set of numbers may actually be the *ratio* of total cholesterol to HDL, which should not fall below 5:1. Lastly, triglycerides: less than 150 mg/dl is normal. I guess I really am a candidate for the statins, with all of those risk factors. If you can think of anything specific I should be asking, post it here and I'll add it to my list. Shari Sampy, Just thought of something else I'd read about PLAQUENIL. And to answer you question, I am not on any steroids. I'd apparently lost it or given it away, so I redid my notes, too. I'm really glad you are seeing such quick action from your nrw rheumie. from Vee Vee, My cholesterol was a tad high at 205. Maybe I could control it better with diet and exercise. I still have a bunch of questions that need answering. We watch my husband's levels---he has mild diabetes. What is plaquenil screening Hydroxychloroquine manufacturer coupons Is quinolone related to plaquenil Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. HDL cholesterol levels are not typically affected. Currently, indapamide is the only thiazide diuretic that has not been shown to adversely affect lipid levels. Loop diuretics share the same pattern as thiazide diuretics; however, some of these drugs have shown a slight decrease in HDL cholesterol. Mar 07, 2008 My cholesterol was 218, which is the lowest it has been in 10 years, additionally my HDL and LDL were both in the normal range. I can not remember a time when my HDL and LDL were in the normal range, probably a good 30 years ago. The only new medication on my list is Plaquenil, does anyone know of a connection between Plaquenil and cholesterol. e.g., someone with NO coronary disease but who has 2 risk factors might be prescribed a drug with an LDL level of 160, which is barely "high". NEW POINT we haven't kicked around: There are people who do all the right things (maintain proper weight, eat properly, exercise, etc.) but can't bring their cholesterol values down, no matter how hard they try. Another thing that affects cholesterol levels: long-term steroid use; moderate-to-high doses will elevate levels. With my best wishes, Vee Vee, I just wanted to thank you for all of your time and effort researching this stuff. has LOWERED the cholesterol guidelines for LDL = bad cholersterol. Hmmmmm....) I think they dropped the guidlelines by at least 30 points. *HDL* is the "good" cholesterol and, for good health, should not be below 40. Sampy, given the above, if you knew WHAT that "205" represents, this might make quite a bit more sense! I have a good friend who does all that---she's a size 2 (! High cholesterol simply runs in her family; and her mother (who had heart problems & is now deceased from Altzheimers) had very high readings also. Is it THEN that you will start taking Plaquenil & a statin, after all your other tests come back? isn't starting me on Plaquenil and statins until AFTER I see him in Sept. I read ALOT on this auto-immune stuff, but not all of it sinks in. Plaquenil cholesterol Treating Lupus with Anti-Malarial Drugs Johns Hopkins., A List of Medications That Increase Cholesterol Levels Plaquenil and liver diseasePlaquenil sanofi ulotkaDrug interaction chloroquine and ibuprofenHydroxychloroquine sle mechanismHonduras chloroquine sensitive Hydroxychloroquine Plaquenil®, especially at the higher standard dose of 400 mg per day, independently decreases the risk of cardiovascular morbidity in people with rheumatoid arthritis. Hydroxychloroquine reduces cardiovascular morbidity risk.. Cholesterol and Plaquenil - Sclero Forums MAIN - Sclero Forums. Can we reduce vascular plaque buildup? - Harvard Health. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine, brand name Plaquenil, is a time-tested and often-used medication that is typically a first line of defense in the treatment of autoimmune conditions such as RA and lupus. Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells a special type of white blood cell which through a convoluted and boring process, causes inflammation.