Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine inhibits autophagy in mice Who can do a plaquenil eye exam Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease Corneal changes including edema and opacities can be symptomless or may cause disturbances such as haloes, blurring of vision or photophobia. They may be transient and are reversible when therapy is discontinued.-Maculopathies and macular degeneration can occur from 3 months to several years of exposure to this drug and may be irreversible. One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can hydroxychloroquine cause vision changes Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs, Hydroxychloroquine Side Effects Common, Severe, Long Term - Chloroquine phosphate shortagePrednisone and hydroxychloroquine interactionCan i take plaquenil with percocet Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. The Risk of Retinal Toxicity with Plaquenil. Protecting your eyesight when taking Plaquenil Lupus Foundation of.. This means many people taking Plaquenil for RA are taking a dose of 400mg a day or higher. Pigment deposits in the retina can cause vision changes, according to Steven Ofner, M. D. of Eugene Oregon Eye Care. Signs of retinal damage include blurry or distorted vision, flashes of light or floaters, or loss of night vision. Find information about common, infrequent and rare side effects of Plaquenil Oral. Both may cause color vision changes, visual field defects, and an optic neuritis an inflammation that damages the optic nerve. Hydroxychloroquine Plaquenil is a used for the treatment of malaria as well as rheumatoid arthritis, lupus, and other autoimmune disorders. The eye effects of this medication are numerous—they include corneal.