I just want to know if this really is nothing in the world of Lupus and inflammation....rheumatologists refuse to consider Lupus,because: 1. They have looked at everything else, and nothing else fits what is going on. My platelet count had been low and went even lower and I had mild anemia for years. I need help, so I don't mind) It was 38 two weeks ago, and it is 52 now. I wish you didn't have this to deal with at such a young age. My doctors deduced I had it several months before my first flare and confirmation by tests that I had lupus. Hydroxychloroquine plaquenil mechanism of action Keyhole hydroxychloroquine Plaquenil que es Chloroquine phosphate mechanism of action Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. A sedimentation rate is a common blood test that is used to detect and monitor inflammation in the body. The sedimentation rate is also called the erythrocyte sedimentation rate because it is a measure of the speed that the red blood cells erythrocytes in a tube of blood fall to the bottom of the tube form sediment. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Someone will be along with information/criteria for diagnosis. There are alot of helpful, smart and supportive people in this forum. God Bless You, Judy FMS won't register an elevated ESR. Keep a diary of all your symptoms, take pictures of any rashes, etc. People with fibro do not usually have abnormal labs and an elevated sed rate means you have inflammation somewhere. It is just an indication that some type of inflammatory process is active. Tests can be negative or positive and vary from test to test and yet you can have lupus. Make sure your rheumatologist has as much information as possible. That is why so many do not get a positive diagnosis for years. Plaquenil increases sed rate Erythrocyte Sedimentation Rate and C-Reactive Protein Old., What Is Sedimentation Rate? Normal Test Levels & What They Mean Hair loss with plaquenil A clinical study compared hydroxychloroquine 400 mg PO once daily vs. placebo in 101 patients over a period of 24 weeks. Significant improvements in joint score, pain, and grip strength but not erythrocyte sedimentation rate ESR were seen in the active drug group. Plaquenil hydroxychloroquine sulfate dose, indications, adverse.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Erythrocyte Sedimentation Rate and C-Reactive Protein Old But Useful.. Too many women getting really sick this year and showing high sedimentation rate. I think there is a new virus or bacteria that has become strong and it is making the autoimmune system get in shock! I was put on prednisone and once I stopped, my sedimentation rate kept going up. In rare cases, hydroxychloroquine can cause visual changes or loss of vision. Such vision problems are more likely to occur in individuals taking high doses for many years, individuals 60 years or older, or those with significant kidney disease. At the recommended dose, development of visual problems due to the medication is rare. Erythrocyte sedimentation rate. This blood test determines the rate at which red blood cells settle to the bottom of a tube in an hour. A faster than normal rate may indicate a systemic disease, such as lupus. The sedimentation rate isn't specific for any one disease.