While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. The studies that do exist show mixed results (some show Nonetheless, despite the lack of clinical studies, rheumatologists feel that hydroxychloroquine may have a potential beneficial effect in helping patients with symptoms of fatigue and achiness, which are common complaints in patients with Sjögren’s. How to quit taking hydroxychloroquine Hydroxychloroquine and ocular toxicity recommendations on screening 2009 Chloroquine bull's eye maculopathy guidelines For most people with Sjogren’s syndrome, treating dry eye and dry mouth are enough to enhance the quality of their lives. But in those who develop joint pain, fatigue, nerve dysfunction, or fibromyalgia, symptoms can be treated with mild medications. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Two drugs approved for dry mouth, pilocarpine Salagen and cevimeline Evoxac, may help dry eyes. While they aren’t approved for dry eyes, your doctor may prescribe them for that purpose. Also, if you take one of these drugs for dry mouth, it may help your eyes. The good news is that hydroxychloroquine targets the immune system without causing an increase in the risk of infection or cancer that can be seen with other immunosuppressant medications. How the drug works is unclear, but recent research has pointed to an inhibitory effect on toll-like receptors that are proteins involved with inflammation. Does plaquenil help dry eyes Plaquenil - thought I was experiencing serious eye., Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Methotrexate and plaquenil for raChloroquine cancer patientsPlaquenil weight gain forumSide effects of plaquenil mayo clinic In addition to dry eyes and mouth, this can result in difficulty breathing and problems with digestive and bowel function. As with most autoimmune illnesses, it is much more common in women than men. Treatment includes artificial tears and saliva and, in more severe cases, immune blockers such as prednisone, Plaquenil and even the cancer medication Methotrexate. Why There's More to Sjogren's Syndrome The Dr. Oz Show. Treatment Options for Sjogren Syndrome Arthritis Foundation. Dry eyes, Sjogren’s and Plaquenil.. Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Summary Dry eyes is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA. Plaquenil is a drug used to treat Rheumatoid Arthritis and Systemic Lupus Erythematosis. It is a very good drug and gives many patients significant relief from their symptoms. Plaquenil related eye complications are not common. Plaquenil can produce pigment changes in the macula of the retina.