So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Hydroxychloroquine skin rash Hydroxychloroquine plaquenil reviews Screening criteria for ocular toxicity of plaquenil I was diagnosed with lupus SLE almost 9 years ago and take prednisone and plaquenil on a daily basis. I work in a building where there are fluorescent lights. I have been running a fever everyday, anywhere from 100-102 since August when I started work again I have the summers off. Lynwood, I can't answer your question about weight gain or loss on plaquenil but I did go off plaquenil a few months ago and haven't been the same since. I regret the decision which had I made because I'd felt pretty well for quite some time and was doing my best to slowly get off as many meds as possible. It works well on the more systemic side effects of RA e.g. pericarditis, pleuritis, fevers, etc. which is why Plaq is also used with lupus patients. I've been on it for about 2 1/2 years now, and won't stop unless I have to since it works well for me, it's cheap, easy to take oral tablet only twice a day, and I'm past the worst of the side. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Running fevers since going off plaquenil Recurrent Fever - When It’s a Virus, When It’s Something More, Plaquenil & Weight Gain/Loss - Chloroquine storage in retina Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. Will you have Withdrawal syndrome with Plaquenil - eHealthMe. PLAQUENIL" Rheumatoid Arthritis Community - Support Group. What is the correct way to discontinue use of plaquenil?. As some of you know I started on Plaquenil 6 weeks ago. After two weeks I stopped it because of liver pain, and we found out I had raised liver enzymes. I stayed off it for two weeks until I could contact my rheumatologist who was on holiday My rheumatologist did not think think the Plaquenil w. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. He can hear the wheezing and believes the Plaquenil is causing Bronchospasm and the cough. He ran a CT scan to ensure it was not Lymphodema in the chest and it came back fine. The MD told me he was not going to pull me off the Plaquenil, because he did not want the RA sypmtoms to worsen.