Plaquenil guidelines for eye monitoring 2016

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  1. commando Guest

    Plaquenil guidelines for eye monitoring 2016


    Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating.

    Chloroquine dosage adult Hydroxychloroquine vs truvada Ocular follow-up in regards to hydroxychloroquine Chloroquine phosphate reef

    The goal of monitoring/screening is to identify early macular damage prior to irreversible vision loss or even before visible signs of bull’s eye maculopathy. And although the current guidelines do not discuss the importance of continuous ocular care with an annual comprehensive eye exam, we believe that it is an essential consideration. 1. Plaquenil and eye exams allie_bf posted For the last few years, my rheumagologist and opthamologist have disagreed on the frequency for eye exams my opthamologist says every year is sufficient, but my rheumatologist still insists every 6 months is what should be done. Screening guidelines were updated this year, with some pertinent changes for our profession to note. Cumulative dose is no longer a risk factor, but more of a tool in the screening of our patients.

    Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area).

    Plaquenil guidelines for eye monitoring 2016

    Plaquenil - Eye Doctor MD, Plaquenil and eye exams" Lupus Community - Support Group

  2. Pros of chloroquine
  3. AAO revised guidelines. The AAO published dosing and screening recommendations for chloroquine and hydroxychloroquine in 2016, revising previous recommendations published in 2011. The current maximum daily HCQ dose recommended by the AAO is 5 mg/kg of real weight. The 2011 guidelines suggested a maximum dose of 6.5 mg/kg of ideal weight.

    • Despite Plaquenil dosing recommendations, retinal toxicity..
    • New Guidelines for Hydroxychloroquine Visual Screening.
    • SARCOIDOSIS TREATMENT GUIDELINES.

    The new guidelines recommend 10-2 automated perimetry, plus at least one of SD-OCT, FAF, or mfERG if they are available. These tests should be performed at baseline and at each subsequent evaluation. Other tests may be considered as well, but are generally insufficiently sensitive to detect early evidence of hydroxychloroquine toxicity. That recommendation was lowered in March 2016 to 5.0 mg per kg of actual body weight, up to a maximum of 400 mg a day. The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity 1. According to these new guidelines, the risk of HCQ retinal toxicity is less than 1 % in the first year of therapy and less than 2 % up to 10 years of therapy.

     
  4. StranNick-36 Moderator

    This article focuses upon hydroxychloroquine retinopathy. Chloroquine was originally used as an anti-malarial therapeutic. Plaquenil causes and treats neuropathy? - NeuroTalk Support. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Risks of Hydroxychloroquine
     
  5. lmk^218 Well-Known Member

    ive put on 45 lbs since starting this medication back in October it is January now so that’s 10lbs a month. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly? RA and Hydroxychloroquine How Effective is it for Rheumatoid.
     
  6. Yegor13 Guest

    Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.

    Retinal Physician - Hydroxychloroquine Maculopathy An Update.
     
  7. artfrom53 New Member

    Seizures with Lupus. - Lupus - Sep 22, 2010 It is a good plan to see a neurologist, I admire your dr. for admitting she/he isn't experienced in seizure tx. Plaquenil and Neurontin have helped me immensely for over 5 yrs. The plaquenil has helped my joint pain, and the neurontin lessens the terrible burning, numbness and tingling in my extremities that I live with most of the time.

    Plaquenil Side Effects Common, Severe, Long Term -