While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "Hydrochloroquine (Plaquenil) has been a blessing for me. Treatment for eye issues after taking plaquenil Plaquenil and sun rash Plaquenil and menstrual cycle Hydroxychloroquine sulfate tablet side effects Summary. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Jun 25, 2013 Hi, although Plaquenil is prescribed for autoimmune diseases, such as yours, it can actually add to/increase the number of the symptoms. Muscle damage and leg pain being just 2 examples. It is great that you have responded so well to the new medication. When starting hydroxychloroquine do symptoms feel worse. got so ill they wanted me to go on chemo based drugs but I did not want that either. so reluctantly went back on the plaquenil. imo its made me worse. I hate it and now cant come off it but cannot bear the fibrio type pain it has given me. now they want me on a drug they use for. I do occasionally experience dry eyes and a little scalp itch but asserting that it's caused by Hydrochloroquine would be anecdotal at best. It took about 5 weeks to take effect but my RA is basically a non factor now. Pain worse after plaquenil Rheumatoid Arthritis and Sleep Arthritis Foundation, Hydroxychloroquine - thigh muscle weakness? Screening criteria for ocular toxicity of plaquenil Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. When starting hydroxychloroquine do symptoms feel.. Plaquenil Side Effects Common, Severe, Long Term -. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Diagnosed with Lupus at age 50 after lots of misdiagnosed ailments. First on prednisone and then told steroid was only temp reduce swelling and Plaquenil prescribed and started at 200 mg twice per. A lower dose may stop them. Do not lower the dose on your own. Plaquenil stays in your body for about 3 months. If you must stop it, it will take a while for the side effects to go away. You should have an eye examination every year to prevent a very rare but serious eye problem.