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    My doctor prescribed me generic Lexapro (escitalopram) for mild situational depression and generalized anxiety. I have read many negative reviews about the generic versus the name brand, but most of those reviews seem to come from people who switched from the name brand to generic mid-treatment and had negative side effects (possibly because the generic and name brand are not EXACTLY the same and their bodies had to readjust to the new medical formulation). Has anyone had positive results beginning their treatment on the generic (as opposed to just switching from name brand to generic)? The generic is only $7 through my insurance, and the name brand is $166! But, I am scared to take the generic if even newbies have terrible reactions. I haven't tried lexapro generic, but I've taken other generic forms of SSRIs. I've had a lot of success with generics, plus they are super cheap! If the generic forms weren't similar enough to the name brand, the FDA would take them off the market. The Food and Drug Administration sees no difference between brand-name and generic medications for depression. Most psychiatrists readily prescribe generics as effective copies of the original. That said, it is not at all rare for patients who switch to a generic from a brand-name medication to experience a difference. Sometimes they feel a return of the old sadness, anxiety, and helplessness that the antidepressant helped to lift. Other times, they get an unusual jolt of the same side effects that hit when they began taking the first drug. There’s not been a “systematic problem” with generic antidepressants, says Jonathan Edward Alpert, MD, Ph D, chief of clinical psychiatry at Massachusetts General Hospital in Boston. But doctors need to be vigilant.” There are scattered reports of people experiencing a return of depression symptoms -- or side effects -- when they go on generics. In one recent study, a group of Canadian psychiatrists described seven cases in which patients with depression were taking Paxil or Celexa.

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